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IUI – Intrauterine inseminati

Intrauterine insemination is a fairly simple method of assisted fertilization with which previously prepared seed material from a male partner is inserted inside the uterus at the time of ovulation, thus increasing the probability for fertilization and conception. It is usually used for couples with so called idiopathic infertility or infertility of unknown origin, problems with ovulation (after we have induced a woman’s ovulation medically) and a basic prerequisite for the application of this method is a reciprocal tubal passage (Oviduct).

How does this process look like?

For the female partner

The insemination can be done in a natural cycle, if a woman has  neat ovulations.

If it is done in a natural cycle, the processed seed material is inserted in the uterus from the 12th to the 15th day of the cycle (the first day of the cycle is always the day when the menstrual bleeding started). In order to determine the accurate ovulation your gynecologist will follow the follicular growth and the thickness and the appearance of the endometrium of the ultrasound which can also be followed with the hormonal blood testing for the LH hormones and estradiol.

During the preparation your gynecologists may decide to stimulate the ovulation with tablets or folliculometric injections with which it will be able to follow the follicular growth which matures the egg cell and at some point decides on HCG injection or injecting a popula standpoint .

The previously prepared sperm is inserted into the uterus 36-40 hours after the standpoint injection .

The gynecologist of human reproduction places a speculum (an instrument used to spread the vaginal wall) into the vagina with a small, thin and flexible catheter and through the cervix the previously prepared material is placed inside the uterus.

By treating the seed or the sperm material, with the so-called gradient method by removing the fluid in which the sperm swims, the best sperm is selected.

The whole process takes a few minutes and it is painless.


For the male partner

The male partner gives seed material or sperm on the day of the insemination that is obtained by a gradient process. In order the material to be in a better quality it is necessary for the male partner to refrain from ejaculation 2-3 days before the insemination.  

The success rate of this method is 15% of the single cycle with the use of ovulation inducing therapy that is greater in younger women.The pregnancy test is done 15 to 21 days after the insemination.  

It is considered that it makes no sense to repeat the procedure more than 4 times if all of the above criteria are met. If the procedure fails the gynecologist for human reproduction will suggest another treatment or even in vitro.